Seasonally seen, I prefer quinoa in warmer temperatures and buckwheat in colder climate.
But that may be a matter of opinion and constitution, since both plants have been cultivated in high altitude regions in the world.
I use quinoa in recipes where usually rice is used. It can’t really substitute the heavenly taste of good rice, but at least it is grain like and mild in taste.
If your histamine tolerance is low quinoa might be the better choice over buckwheat. I stick to quinoa in times my symptoms or eczema occur.